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Daniel R Doerge Selected Research

Isoflavones

2/2020(±)-Equol does not interact with genistein on estrogen-dependent breast tumor growth.
8/2015Isoflavones in soy flour diet have different effects on whole-genome expression patterns than purified isoflavone mix in human MCF-7 breast tumors in ovariectomized athymic nude mice.
4/2015Dietary soy isoflavones increase metastasis to lungs in an experimental model of breast cancer with bone micro-tumors.
4/2012Low-dose dietary genistein negates the therapeutic effect of tamoxifen in athymic nude mice.
7/2011Bioavailability of soy isoflavones through placental/lactational transfer and soy food.
7/2010Design and baseline characteristics of the soy phytoestrogens as replacement estrogen (SPARE) study--a clinical trial of the effects of soy isoflavones in menopausal women.
7/2010Acute and chronic effects of oral genistein administration in neonatal mice.
1/2010Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells.
11/2008Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human breast cancer cells (MCF-7Ca) in vivo.
6/2007Soy isoflavones enhance radiotherapy in a metastatic prostate cancer model.
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Daniel R Doerge Research Topics

Disease

45Neoplasms (Cancer)
02/2020 - 05/2002
23Body Weight (Weight, Body)
01/2018 - 12/2002
18Breast Neoplasms (Breast Cancer)
02/2020 - 05/2002
9Carcinogenesis
05/2018 - 06/2002
6Neoplasm Metastasis (Metastasis)
01/2016 - 07/2004
6Prostatic Neoplasms (Prostate Cancer)
07/2011 - 07/2004
3Carcinoma (Carcinomatosis)
11/2012 - 10/2004
3Osteoporosis
07/2010 - 09/2002
3Endometrial Neoplasms (Endometrial Cancer)
07/2004 - 03/2003
2Weight Gain
02/2016 - 01/2008
2Liver Cell Adenoma (Hepatocellular Adenoma)
11/2012 - 01/2005
2Necrosis
06/2012 - 10/2004
2Hyperplasia
01/2010 - 12/2002
2Chromosome Aberrations (Chromosome Abnormalities)
02/2009 - 02/2007
2Obesity
05/2008 - 10/2007
2Lymphatic Metastasis
06/2007 - 07/2006
2Adenocarcinoma
02/2004 - 10/2002
1Bone Resorption
01/2022
1Brain Diseases (Brain Disorder)
03/2018
1Cognitive Dysfunction
03/2018
1Liver Neoplasms (Liver Cancer)
01/2018
1Malignant Mesothelioma
01/2017
1Leukemia
01/2017
1Cholangiocarcinoma
01/2017
1Fatty Liver
02/2016
1Hepatocellular Carcinoma (Hepatoma)
01/2016
1Acute Kidney Injury (Acute Renal Failure)
08/2013
1Inflammation (Inflammations)
06/2012
1Hyperthermia
03/2012
1Methemoglobinemia
10/2011
1B-Cell Lymphoma (Lymphoma, B Cell)
10/2011
1Hot Flashes
07/2011
1Alzheimer Disease (Alzheimer's Disease)
01/2011
1Tauopathies
01/2011
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2011

Drug/Important Bio-Agent (IBA)

20IsoflavonesIBA
02/2020 - 05/2002
18GenisteinIBA
02/2020 - 05/2002
17Estrogens (Estrogen)FDA Link
02/2020 - 05/2002
10DNA AdductsIBA
09/2013 - 09/2003
8Estrogen ReceptorsIBA
01/2016 - 06/2002
8TamoxifenFDA LinkGeneric
04/2012 - 05/2002
7furanIBA
03/2017 - 02/2012
6ArsenicIBA
11/2019 - 01/2018
6Estrogen Receptor Modulators (Antiestrogen)IBA
04/2012 - 05/2002
5EquolIBA
02/2020 - 09/2004
5glycidamideIBA
11/2012 - 06/2004
4CarcinogensIBA
01/2018 - 02/2004
4Proteins (Proteins, Gene)FDA Link
12/2016 - 10/2006
4LipidsIBA
02/2016 - 09/2002
4daidzeinIBA
04/2015 - 11/2005
4DNA (Deoxyribonucleic Acid)IBA
06/2012 - 03/2003
4MutagensIBA
02/2012 - 09/2003
4riddelliineIBA
01/2006 - 07/2002
3Hormones (Hormone)IBA
01/2022 - 03/2003
3Drinking WaterIBA
08/2019 - 01/2005
3Pyrrolizidine AlkaloidsIBA
09/2013 - 09/2003
3Biomarkers (Surrogate Marker)IBA
09/2013 - 02/2005
3Messenger RNA (mRNA)IBA
04/2012 - 09/2004
3Phytoestrogens (Phytoestrogen)IBA
05/2008 - 09/2004
2Estradiol (Delestrogen)FDA LinkGeneric
01/2016 - 02/2004
2Letrozole (Femara)FDA LinkGeneric
01/2016 - 11/2008
2Aromatase InhibitorsIBA
01/2016 - 11/2008
2GlucuronidesIBA
10/2015 - 09/2015
2Sulfates (Sulfates, Inorganic)IBA
10/2015 - 09/2015
2Progesterone Receptors (Progesterone Receptor)IBA
04/2012 - 02/2004
2Cyclin D1IBA
04/2012 - 05/2002
2Caspase 3 (Caspase-3)IBA
10/2011 - 10/2006
2A-Form DNA (A-DNA)IBA
01/2011 - 02/2008
2Epoxy Compounds (Epoxides)IBA
06/2010 - 06/2004
2Aromatase (CYP19)IBA
11/2008 - 09/2004
2NucleotidesIBA
11/2006 - 03/2003
1Tartrate-Resistant Acid PhosphataseIBA
01/2022
1isoliquiritigenin (GU 17)IBA
01/2022
1arseniteIBA
01/2018
1MicroRNAs (MicroRNA)IBA
12/2016
1LuciferasesIBA
04/2015
1Indicators and Reagents (Reagents)IBA
04/2015
1Soybean Proteins (Soy Protein)IBA
03/2015
1ErbB Receptors (EGF Receptor)IBA
03/2015
1Histones (Histone)IBA
06/2014
1Lysine (L-Lysine)FDA Link
06/2014
1ChromatinIBA
06/2014
1bisphenol AIBA
05/2014
1Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
09/2013
1Biological ProductsIBA
09/2013
1melamineIBA
08/2013
1Uric Acid (Urate)IBA
08/2013
1cyanuric acidIBA
08/2013
1Codon (Codons)IBA
11/2012
1PyrimidinesIBA
06/2012
1PurinesIBA
06/2012
1Dopamine (Intropin)FDA LinkGeneric
03/2012
1AmphetaminesIBA
03/2012
1Benzocaine (Americaine)FDA Link
10/2011
1MethemoglobinIBA
10/2011
1GlucosidesIBA
01/2011

Therapy/Procedure

5Therapeutics
04/2012 - 05/2002
3Chemoprevention
07/2011 - 09/2002
2Ovariectomy (Oophorectomy)
02/2016 - 02/2004
2Radiotherapy
06/2007 - 07/2006